| Solution Information | help | |
| Enzyme: | Signal transducer and activator of transcription 1-alpha/beta | |
| inhibitor: | BDBM67111 | |
| substrate: | n/a | |
| Solution Type: | Aqueous | |
| pH at Preparation: | n/a | |
| Temp. Prep.: | n/a | |
| Comments: | Assay Overview: The purpose of this assay is to determine dose response curves for powder samples of compounds identified as active in a previous set of experiments entitled, "Primary cell-based high throughput screening assay to measure STAT1 inhibition" (PubChem AID 920) and that confirmed activity in a set of experiments entitled, "Confirmation cell-based high throughput screening assay to measure STAT1 inhibition" (AID 1263). The compounds selected for testing in this AID met the following criteria: 1) they were declared active in AID 920 and AID 1263; 2) they were declared inactive in a set of experiments entitled, "Primary cell-based high throughput screening assay to measure STAT3 inhibition" (AID 862); 3) they were inactive in a set of experiments entitled, "Counterscreen assay for STAT1 inhibitors: cell-based high throughput assay to measure NF-kappaB inhibition" (AID 1303); and 4) they were inactive in a set of experiments entitled, "Counterscreen assay for STAT1 inhibitors | |
| If you find an error in this entry please send us an E-mail | ||